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Diverse genetic error modes constrain large-scale bio-based production

A transition toward sustainable bio-based chemical production is important for green growth. However, productivity and yield frequently decrease as large-scale microbial fermentation progresses, commonly ascribed to phenotypic variation. Yet, given the high metabolic burden and toxicities, evolution...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rugbjerg, Peter, Myling-Petersen, Nils, Porse, Andreas, Sarup-Lytzen, Kira, Sommer, Morten O. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820350/
https://ncbi.nlm.nih.gov/pubmed/29463788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03232-w
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