Quantifying the fitness cost of HIV-1 drug resistance mutations through phylodynamics

Drug resistant HIV is a major threat to the long-term efficacy of antiretroviral treatment. Around 10% of ART-naïve patients in Europe are infected with drug-resistant HIV type 1. Hence it is important to understand the dynamics of transmitted drug resistance evolution. Thanks to routinely performed...

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Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: Kühnert, Denise, Kouyos, Roger, Shirreff, George, Pečerska, Jūlija, Scherrer, Alexandra U., Böni, Jürg, Yerly, Sabine, Klimkait, Thomas, Aubert, Vincent, Günthard, Huldrych F., Stadler, Tanja, Bonhoeffer, Sebastian
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877888/
https://ncbi.nlm.nih.gov/pubmed/29462208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006895
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