Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis

Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea by evading innate immunity. Colonizing the mucosa of the reproductive tract depends on the bacterial outer membrane porin, PorB, which is essential for ion and nutrient uptake. PorB is also targeted to host mitochondria and reg...

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Vydáno v:PLoS Pathog
Hlavní autoři: Deo, Pankaj, Chow, Seong H., Hay, Iain D., Kleifeld, Oded, Costin, Adam, Elgass, Kirstin D., Jiang, Jhih-Hang, Ramm, Georg, Gabriel, Kipros, Dougan, Gordon, Lithgow, Trevor, Heinz, Eva, Naderer, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877877/
https://ncbi.nlm.nih.gov/pubmed/29601598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006945
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