Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis

Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea by evading innate immunity. Colonizing the mucosa of the reproductive tract depends on the bacterial outer membrane porin, PorB, which is essential for ion and nutrient uptake. PorB is also targeted to host mitochondria and reg...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Deo, Pankaj, Chow, Seong H., Hay, Iain D., Kleifeld, Oded, Costin, Adam, Elgass, Kirstin D., Jiang, Jhih-Hang, Ramm, Georg, Gabriel, Kipros, Dougan, Gordon, Lithgow, Trevor, Heinz, Eva, Naderer, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877877/
https://ncbi.nlm.nih.gov/pubmed/29601598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006945
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