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Saturating Mutagenesis of an Essential Gene: a Majority of the Neisseria gonorrhoeae Major Outer Membrane Porin (PorB) Is Mutable

The major outer membrane porin (PorB) of Neisseria gonorrhoeae is an essential protein that mediates ion exchange between the organism and its environment and also plays multiple roles in human host pathogenesis. To facilitate structure-function studies of porin's multiple roles, we performed s...

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Bibliografiske detaljer
Main Authors: Chen, Adrienne, Seifert, H. Steven
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911144/
https://ncbi.nlm.nih.gov/pubmed/24244002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01073-13
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