CpG ODN1826 as a Promising Mucin1-Maltose-Binding Protein Vaccine Adjuvant Induced DC Maturation and Enhanced Antitumor Immunity

Mucin 1 (MUC1), being an oncogene, is an attractive target in tumor immunotherapy. Maltose binding protein (MBP) is a potent built-in adjuvant to enhance protein immunogenicity. Thus, a recombinant MUC1 and MBP antitumor vaccine (M-M) was constructed in our laboratory. To enhance the antitumor immun...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Jie, Jing, Zhang, Yixin, Zhou, Hongyue, Zhai, Xiaoyu, Zhang, Nannan, Yuan, Hongyan, Ni, Weihua, Tai, Guixiang
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877781/
https://ncbi.nlm.nih.gov/pubmed/29558459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030920
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