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Effects of Mutations and Ligands on the Thermostability of the l-Arginine/Agmatine Antiporter AdiC and Deduced Insights into Ligand-Binding of Human l-Type Amino Acid Transporters

The l-arginine/agmatine transporter AdiC is a prokaryotic member of the SLC7 family, which enables pathogenic enterobacteria to survive the extremely acidic gastric environment. Wild-type AdiC from Escherichia coli, as well as its previously reported point mutants N22A and S26A, were overexpressed h...

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Опубликовано в: :Int J Mol Sci
Главные авторы: Ilgü, Hüseyin, Jeckelmann, Jean-Marc, Colas, Claire, Ucurum, Zöhre, Schlessinger, Avner, Fotiadis, Dimitrios
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877779/
https://ncbi.nlm.nih.gov/pubmed/29558430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030918
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