Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles

Progressive cerebral accumulation of tau aggregates is a defining feature of Alzheimer’s disease (AD). A popular theory that seeks to explain the apparent spread of neurofibrillary tangle pathology proposes that aggregated tau is passed from neuron to neuron. Such a templated seeding process require...

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Publicat a:Int J Mol Sci
Autors principals: Guix, Francesc X., Corbett, Grant T., Cha, Diana J., Mustapic, Maja, Liu, Wen, Mengel, David, Chen, Zhicheng, Aikawa, Elena, Young-Pearse, Tracy, Kapogiannis, Dimitrios, Selkoe, Dennis J., Walsh, Dominic M.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877524/
https://ncbi.nlm.nih.gov/pubmed/29495441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030663
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