Evaluation of a dimeric-cRGD peptide for targeted PET-CT imaging of peripheral angiogenesis in diabetic mice

The α(V) β(3) integrin plays an important role in many physiological functions and pathological disorders. α(V) β(3) is minimally expressed in normal quiescent endothelial cells, but significantly upregulated during neovascularization. In this study, we evaluated a (64)Cu-labeled dimeric cRGD tracer...

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Published in:Sci Rep
Main Authors: Hedhli, Jamila, Slania, Stephanie L. L., Płoska, Agata, Czerwinski, Andrzej, Konopka, Christian J., Wozniak, Marcin, Banach, Maciej, Dobrucki, Iwona T., Kalinowski, Leszek, Dobrucki, Lawrence W.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876368/
https://ncbi.nlm.nih.gov/pubmed/29599497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23372-9
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