Single-cell transcriptomics reveals gene signatures and alterations associated with aging in distinct neural stem/progenitor cell subpopulations

Aging associated cognitive decline has been linked to dampened neural stem/progenitor cells (NSC/NPCs) activities manifested by decreased proliferation, reduced propensity to produce neurons, and increased differentiation into astrocytes. While gene transcription changes objectively reveal molecular...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Shi, Zhanping, Geng, Yanan, Liu, Jiping, Zhang, Huina, Zhou, Liqiang, Lin, Quan, Yu, Juehua, Zhang, Kunshan, Liu, Jie, Gao, Xinpei, Zhang, Chunxue, Yao, Yinan, Zhang, Chong, Sun, Yi E.
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876182/
https://ncbi.nlm.nih.gov/pubmed/28748452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-017-0450-2
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