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Selective Proton-Observed, Carbon-Edited (selPOCE) MRS method for measurement of glutamate and glutamine (13)C-labeling in the human frontal cortex

PURPOSE: (13)C magnetic resonance spectroscopy (MRS) in combination with infusion of (13)C-labeled substrates has led to unique insights into human brain metabolism and neurotransmitter cycling. However, the low sensitivity of direct (13)C MRS and high radiofrequency (RF) power requirements has limi...

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Publicado en:Magn Reson Med
Main Authors: De Feyter, Henk M., Herzog, Raimund I., Steensma, Bart R., Klomp, Dennis W. J., Brown, Peter B., Mason, Graeme F., Rothman, Douglas L., de Graaf, Robin A
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876108/
https://ncbi.nlm.nih.gov/pubmed/29134686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.27003
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