Superparamagnetic iron oxide nanoparticles modified with polyethylenimine and galactose for siRNA targeted delivery in hepatocellular carcinoma therapy

INTRODUCTION: A safe and effective in vivo siRNA delivery system is a prerequisite for liver tumor treatment based on siRNA cancer therapeutics. Nanoparticles based on superparamagnetic iron oxide (SPIO) provide a promising delivery system. In this study, we aimed to explore a novel nanoparticle, wh...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Yang, Zhen, Duan, Juanli, Wang, Jianlin, Liu, Qi, Shang, Runze, Yang, Xisheng, Lu, Peng, Xia, Congcong, Wang, Lin, Dou, Kefeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2018
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875409/
https://ncbi.nlm.nih.gov/pubmed/29618926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S155537
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