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Folic acid-functionalized polyethylenimine superparamagnetic iron oxide nanoparticles as theranostic agents for magnetic resonance imaging and PD-L1 siRNA delivery for gastric cancer

Programmed death ligand-1 (PD-L1), which is highly expressed in gastric cancers, interacts with programmed death-1 (PD-1) on T cells and is involved in T-cell immune resistance. To increase the therapeutic safety and accuracy of PD-1/PD-L1 blockade, RNA interference through targeted gene delivery wa...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Luo, Xin, Peng, Xia, Hou, Jingying, Wu, Shuyun, Shen, Jun, Wang, Lingyun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536232/
https://ncbi.nlm.nih.gov/pubmed/28794626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S137245
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