Autoantibodies in Serum of Systemic Scleroderma Patients: Peptide-Based Epitope Mapping Indicates Increased Binding to Cytoplasmic Domains of CXCR3

Systemic sclerosis (SSc) is a severe chronic autoimmune disease with high morbidity and mortality. Sera of patients with SSc contain a large variety of autoantibody (aab) reactivities. Among these are functionally active aab that bind to G protein-coupled receptors (GPCR) such as C-X-C motif chemoki...

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Vydáno v:Front Immunol
Hlavní autoři: Recke, Andreas, Regensburger, Ann-Katrin, Weigold, Florian, Müller, Antje, Heidecke, Harald, Marschner, Gabriele, Hammers, Christoph M., Ludwig, Ralf J., Riemekasten, Gabriela
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874968/
https://ncbi.nlm.nih.gov/pubmed/29623076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00428
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