Antibodies against chemokine receptors CXCR3 and CXCR4 predict progressive deterioration of lung function in patients with systemic sclerosis

BACKGROUND: The chemokine receptors CXCR3 and CXCR4 are involved in the pathogenesis of fibrosis, a key feature of systemic sclerosis (SSc). It is hypothesized that immunoglobulin (Ig)G antibodies (abs) against these two receptors are present in patients with SSc and are associated with clinical fin...

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Bibliographic Details
Published in:Arthritis Res Ther
Main Authors: Weigold, Florian, Günther, Jeannine, Pfeiffenberger, Moritz, Cabral-Marques, Otavio, Siegert, Elise, Dragun, Duska, Philippe, Aurélie, Regensburger, Ann-Katrin, Recke, Andreas, Yu, Xinhua, Petersen, Frank, Catar, Rusan, Biesen, Robert, Hiepe, Falk, Burmester, Gerd R., Heidecke, Harald, Riemekasten, Gabriela
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863842/
https://ncbi.nlm.nih.gov/pubmed/29566745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1545-8
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