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Microscale 3D Liver Bioreactor for In Vitro Hepatotoxicity Testing under Perfusion Conditions

The accurate prediction of hepatotoxicity demands validated human in vitro models that can close the gap between preclinical animal studies and clinical trials. In this study we investigated the response of primary human liver cells to toxic drug exposure in a perfused microscale 3D liver bioreactor...

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Podrobná bibliografie
Vydáno v:Bioengineering (Basel)
Hlavní autoři: Freyer, Nora, Greuel, Selina, Knöspel, Fanny, Gerstmann, Florian, Storch, Lisa, Damm, Georg, Seehofer, Daniel, Foster Harris, Jennifer, Iyer, Rashi, Schubert, Frank, Zeilinger, Katrin
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874890/
https://ncbi.nlm.nih.gov/pubmed/29543727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering5010024
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