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Effect of Pyruvate Decarboxylase Knockout on Product Distribution Using Pichia pastoris (Komagataella phaffii) Engineered for Lactic Acid Production

Lactic acid is the monomer unit of the bioplastic poly-lactic acid (PLA). One candidate organism for lactic acid production is Pichia pastoris, a yeast widely used for heterologous protein production. Nevertheless, this yeast has a poor fermentative capability that can be modulated by controlling ox...

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Detalhes bibliográficos
Publicado no:Bioengineering (Basel)
Main Authors: Melo, Nadiele T. M., Mulder, Kelly C. L., Nicola, André Moraes, Carvalho, Lucas S., Menino, Gisele S., Mulinari, Eduardo, Parachin, Nádia S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874883/
https://ncbi.nlm.nih.gov/pubmed/29462904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering5010017
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