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Pharmacological Agents Targeting the Cellular Prion Protein
Prion diseases are associated with the conversion of the cellular prion protein (PrP(C)), a glycoprotein expressed at the surface of a wide variety of cell types, into a misfolded conformer (the scrapie form of PrP, or PrP(Sc)) that accumulates in brain tissues of affected individuals. PrP(Sc) is a...
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| Publié dans: | Pathogens |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5874753/ https://ncbi.nlm.nih.gov/pubmed/29518975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens7010027 |
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