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Pharmacological Agents Targeting the Cellular Prion Protein

Prion diseases are associated with the conversion of the cellular prion protein (PrP(C)), a glycoprotein expressed at the surface of a wide variety of cell types, into a misfolded conformer (the scrapie form of PrP, or PrP(Sc)) that accumulates in brain tissues of affected individuals. PrP(Sc) is a...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pathogens
Egile Nagusiak: Barreca, Maria Letizia, Iraci, Nunzio, Biggi, Silvia, Cecchetti, Violetta, Biasini, Emiliano
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874753/
https://ncbi.nlm.nih.gov/pubmed/29518975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens7010027
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