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Role of Akt Isoforms Controlling Cancer Stem Cell Survival, Phenotype and Self-Renewal

The cancer stem cell (CSC) hypothesis suggests that tumours are maintained by a subpopulation of cells with stem cell properties. Although the existence of CSCs was initially described in human leukaemia, less evidence exists for CSCs in solid tumours. Recently, a CD133+ cell subpopulation was isola...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Rivas, Sergio, Gómez-Oro, Carla, Antón, Inés M., Wandosell, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874686/
https://ncbi.nlm.nih.gov/pubmed/29518912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines6010029
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