Large Cell Neuroendocrine Carcinoma Harboring an Anaplastic Lymphoma Kinase (ALK) Rearrangement with Response to Alectinib

Anaplastic lymphoma kinase (ALK) rearrangement is most commonly observed in lung adenocarcinoma in a subset of lung cancer. Large cell neuroendocrine carcinoma (LCNEC) harboring an ALK rearrangement is very rare. Based on the findings from a transbronchial lung biopsy, a 75-year-old non-smoking woma...

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Bibliographic Details
Published in:Intern Med
Main Authors: Hayashi, Nobuyoshi, Fujita, Akihisa, Saikai, Toyohiro, Takabatake, Hirotugu, Sotoshiro, Mie, Sekine, Kyuutarou, Kawana, Akihiko
Format: Artigo
Language:Inglês
Published: The Japanese Society of Internal Medicine 2017
Subjects:
Case Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874345/
https://ncbi.nlm.nih.gov/pubmed/29151522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2169/internalmedicine.9368-17
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