Hypersensitivity of Prelimbic Cortex Neurons Contributes to Aggravated Nociceptive Responses in Rats With Experience of Chronic Inflammatory Pain

Previous experience of chronic pain causes enhanced responses to upcoming noxious events in both humans and animals, but the underlying mechanisms remain unclear. In the present study, we found that rats with complete Freund’s adjuvant (CFA)-induced chronic inflammatory pain experience exhibited agg...

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Bibliographic Details
Published in:Front Mol Neurosci
Main Authors: Fan, Xiao-Cen, Fu, Su, Liu, Feng-Yu, Cui, Shuang, Yi, Ming, Wan, You
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874315/
https://ncbi.nlm.nih.gov/pubmed/29623029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00085
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