Deactivation of excitatory neurons in the prelimbic cortex via Cdk5 promotes pain sensation and anxiety

The medial prefrontal cortex (mPFC) is implicated in processing sensory-discriminative and affective pain. Nonetheless, the underlying mechanisms are poorly understood. Here we demonstrate a role for excitatory neurons in the prelimbic cortex (PL), a sub-region of mPFC, in the regulation of pain sen...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wang, Guo-Qiang, Cen, Cheng, Li, Chong, Cao, Shuai, Wang, Ning, Zhou, Zheng, Liu, Xue-Mei, Xu, Yu, Tian, Na-Xi, Zhang, Ying, Wang, Jun, Wang, Li-Ping, Wang, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518290/
https://ncbi.nlm.nih.gov/pubmed/26179626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8660
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