Enhancer variants reveal a conserved transcription factor network governed by PU.1 during osteoclast differentiation

Genome-wide association studies (GWASs) have been instrumental in understanding complex phenotypic traits. However, they have rarely been used to understand lineage-specific pathways and functions that contribute to the trait. In this study, by integrating lineage-specific enhancers from mesenchymal...

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Опубликовано в: :Bone Res
Главные авторы: Carey, Heather A., Hildreth, Blake E., Geisler, Jennifer A., Nickel, Mara C., Cabrera, Jennifer, Ghosh, Sankha, Jiang, Yue, Yan, Jing, Lee, James, Makam, Sandeep, Young, Nicholas A., Valiente, Giancarlo R., Jarjour, Wael N., Huang, Kun, Rosol, Thomas J., Toribio, Ramiro E., Charles, Julia F., Ostrowski, Michael C., Sharma, Sudarshana M.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874256/
https://ncbi.nlm.nih.gov/pubmed/29619268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-018-0011-1
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