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Alu-mediated inactivation of the human CMP- N-acetylneuraminic acid hydroxylase gene

Inactivation of the CMP-N-acetylneuraminic acid hydroxylase gene has provided an example of human-specific genomic mutation that results in a widespread biochemical difference between human and nonhuman primates. We have found that, although a region containing a 92-bp exon and an AluSq element in t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Hayakawa, Toshiyuki, Satta, Yoko, Gagneux, Pascal, Varki, Ajit, Takahata, Naoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC58741/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11562455/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.191268198
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