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Interaction of HuDA and PABP at 5'UTR of mouse insulin2 regulates insulin biosynthesis

Understanding the regulation of insulin biosynthesis is important as it plays a central role in glucose metabolism. The mouse insulin gene2 (Ins2) has two splice variants; long (Ins2L) and short (Ins2S), that differ only in their 5’UTR sequence and Ins2S is the major transcript which translate more...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Pandey, Poonam R., Sarwade, Rucha D., Khalique, Abdul, Seshadri, Vasudevan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874046/
https://ncbi.nlm.nih.gov/pubmed/29590218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194482
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