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miR-196b-Mediated Translation Regulation of Mouse Insulin2 via the 5′UTR

The 5′ and the 3′ untranslated regions (UTR) of the insulin genes are very well conserved across species. Although microRNAs (miRNAs) are known to regulate insulin secretion process, direct regulation of insulin biosynthesis by miRNA has not been reported. Here, we show that mouse microRNA miR-196b...

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Hlavní autoři: Panda, Amaresh C., Sahu, Itishri, Kulkarni, Shardul D., Martindale, Jennifer L., Abdelmohsen, Kotb, Vindu, Arya, Joseph, Jomon, Gorospe, Myriam, Seshadri, Vasudevan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086887/
https://ncbi.nlm.nih.gov/pubmed/25003985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101084
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