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Mechanisms and functions of cellular senescence

Cellular senescence is a highly stable cell cycle arrest that is elicited in response to different stresses. By imposing a growth arrest, senescence limits the replication of old or damaged cells. Besides exiting the cell cycle, senescent cells undergo many other phenotypic alterations such as metab...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Herranz, Nicolás, Gil, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873888/
https://ncbi.nlm.nih.gov/pubmed/29608137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI95148
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