AMP-activated protein kinase protects against necroptosis via regulation of Keap1-PGAM5 complex

BACKGROUND: The AMP-activated protein kinase (AMPK) plays critical roles in growth regulation and metabolism reprogramming. AMPK activation protects cells against apoptosis from injury in different cell and animal models. However, its function in necroptosis remains largely unclear. METHODS AND RESU...

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Publicado en:Int J Cardiol
Main Authors: Wang, Yi-Shu, Yu, Peng, Wang, Yong, Zhang, Jing, Hang, Wei, Yin, Zhi-Xian, Liu, Gang, Chen, Jianfeng, Werle, Kaitlin D., Quan, Cheng-Shi, Gao, Hang, Zeng, Qinghua, Cui, Rutao, Liang, Jiyong, Ding, Qiang, Li, Yu-Lin, Xu, Zhi-Xiang
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873603/
https://ncbi.nlm.nih.gov/pubmed/29579593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2018.01.036
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