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Tethering of Lsh at the Oct4 locus promotes gene repression associated with epigenetic changes

Lsh is a chromatin remodeling factor that regulates DNA methylation and chromatin function in mammals. The dynamics of these chromatin changes and whether they are directly controlled by Lsh remain unclear. To understand the molecular mechanisms of Lsh chromatin controlled regulation of gene express...

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Vydáno v:Epigenetics
Hlavní autoři: Ren, Jianke, Hathaway, Nathaniel A., Crabtree, Gerald R., Muegge, Kathrin
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873361/
https://ncbi.nlm.nih.gov/pubmed/28621576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1338234
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