Infusion of donor-derived CD8(+) memory T cells for relapse following allogeneic hematopoietic cell transplantation

Murine models showed that CD8(+)CD44(hi) memory T (T(M)) cells could eradicate malignant cells without inducing graft-versus-host disease (GVHD). We evaluated the feasibility and safety of infusing freshly isolated and purified donor-derived phenotypic CD8(+) T(M) cells into adults with disease rela...

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Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Muffly, Lori, Sheehan, Kevin, Armstrong, Randall, Jensen, Kent, Tate, Keri, Rezvani, Andrew R., Miklos, David, Arai, Sally, Shizuru, Judith, Johnston, Laura, Meyer, Everett, Weng, Wen-Kai, Laport, Ginna G., Negrin, Robert S., Strober, Sam, Lowsky, Robert
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2018
Sujets:
Clinical Trials and Observations
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873230/
https://ncbi.nlm.nih.gov/pubmed/29572391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017012104
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