Epigenetic versus Genetic Deregulation of the KEAP1/NRF2 Axis in Solid Tumors: Focus on Methylation and Noncoding RNAs

Oxidative and electrophilic changes in cells are mainly coordinated by the KEAP1/NRF2 (Kelch-like erythroid-derived cap-n-collar homology- (ECH-) associated protein-1/nuclear factor (erythroid-derived 2)-like 2) axis. The physical interaction between these two proteins promotes the expression of sev...

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Bibliografiske detaljer
Udgivet i:Oxid Med Cell Longev
Main Authors: Fabrizio, F. P., Sparaneo, A., Trombetta, D., Muscarella, L. A.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2018
Fag:
Review Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872633/
https://ncbi.nlm.nih.gov/pubmed/29643973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2492063
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