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The Hypoxia-Mimetic Agent Cobalt Chloride Differently Affects Human Mesenchymal Stem Cells in Their Chondrogenic Potential

Adult stem cells are a promising cell source for cartilage regeneration. They resided in a special microenvironment known as the stem-cell niche, characterized by the presence of low oxygen concentration. Cobalt chloride (CoCl(2)) imitates hypoxia in vitro by stabilizing hypoxia-inducible factor-alp...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Teti, Gabriella, Focaroli, Stefano, Salvatore, Viviana, Mazzotti, Eleonora, Ingra', Laura, Mazzotti, Antonio, Falconi, Mirella
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872594/
https://ncbi.nlm.nih.gov/pubmed/29731777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3237253
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