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Changes in the gene expression of co-cultured human fibroblast cells and osteosarcoma cells: the role of microenvironment

BACKGROUND: The progression of malignant tumors does not depend exclusively on the autonomous properties of cancer cells; it is also influenced by tumor stroma reactivity and is under strict microenvironmental control. By themselves, stromal cells are not malignant, and they maintain normal tissue s...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Salvatore, Viviana, Focaroli, Stefano, Teti, Gabriella, Mazzotti, Antonio, Falconi, Mirella
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745706/
https://ncbi.nlm.nih.gov/pubmed/26418748
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