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Screening of E. coli β-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization

The characteristic of interaction with various enzymes and processivity-promoting nature during DNA replication makes β-clamp an important drug target. Helicobacter pylori (H. pylori) have several unique features in DNA replication machinery that makes it different from other microorganisms. To find...

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Bibliographic Details
Published in:Antibiotics (Basel)
Main Authors: Pandey, Preeti, Verma, Vijay, Dhar, Suman Kumar, Gourinath, Samudrala
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872116/
https://ncbi.nlm.nih.gov/pubmed/29324718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics7010005
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