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Structural insight into β-Clamp and its interaction with DNA Ligase in Helicobacter pylori
Helicobacter pylori, a gram-negative and microaerophilic bacterium, is the major cause of chronic gastritis, gastric ulcers and gastric cancer. Owing to its central role, DNA replication machinery has emerged as a prime target for the development of antimicrobial drugs. Here, we report 2Å structure...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4976356/ https://ncbi.nlm.nih.gov/pubmed/27499105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31181 |
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