Structural insight into β-Clamp and its interaction with DNA Ligase in Helicobacter pylori

Helicobacter pylori, a gram-negative and microaerophilic bacterium, is the major cause of chronic gastritis, gastric ulcers and gastric cancer. Owing to its central role, DNA replication machinery has emerged as a prime target for the development of antimicrobial drugs. Here, we report 2Å structure...

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Vydáno v:Sci Rep
Hlavní autoři: Pandey, Preeti, Tarique, Khaja Faisal, Mazumder, Mohit, Rehman, Syed Arif Abdul, kumari, Nilima, Gourinath, Samudrala
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976356/
https://ncbi.nlm.nih.gov/pubmed/27499105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31181
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