Sample-Index Misassignment Impacts Tumour Exome Sequencing

Sample pooling enabled by dedicated indexes is a common strategy for cost-effective and robust high-throughput sequencing. Index misassignment leading to mutual contamination between pooled samples has however been described as a general problem of the latest Illumina sequencing instruments utilizin...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Vodák, Daniel, Lorenz, Susanne, Nakken, Sigve, Aasheim, Lars Birger, Holte, Harald, Bai, Baoyan, Myklebost, Ola, Meza-Zepeda, Leonardo A., Hovig, Eivind
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871786/
https://ncbi.nlm.nih.gov/pubmed/29593270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23563-4
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