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Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase
G protein-coupled receptors (GPCRs), G proteins and adenylyl cyclase (AC) comprise one of the most studied transmembrane cell signaling pathways. However, it is unknown whether the ligand-dependent interactions between these signaling molecules are based on random collisions or the rearrangement of...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5871782/ https://ncbi.nlm.nih.gov/pubmed/29593213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03522-3 |
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