Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice

Temporal and spatial-specific regulation of pluripotency networks is largely dependent on the precise modifications of core transcription factors. Misregulation of glutamylation is implicated in severe physiological abnormalities. However, how glutamylation regulates cell reprogramming and pluripote...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ye, Buqing, Liu, Benyu, Hao, Lu, Zhu, Xiaoxiao, Yang, Liuliu, Wang, Shuo, Xia, Pengyan, Du, Ying, Meng, Shu, Huang, Guanling, Qin, Xiwen, Wang, Yanying, Yan, Xinlong, Li, Chong, Hao, Junfeng, Zhu, Pingping, He, Luyun, Tian, Yong, Fan, Zusen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871780/
https://ncbi.nlm.nih.gov/pubmed/29593216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03008-2
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