Resolvin E1 Inhibits Osteoclastogenesis and Bone Resorption by Suppressing IL-17-induced RANKL Expression in Osteoblasts and RANKL-induced Osteoclast Differentiation

BACKGROUND: Resolvin E1 (RvE1) derived from the ω-3 polyunsaturated fatty acid eicosapentaenoic acid is known to be a potent pro-resolving lipid mediator that prevents chronic inflammation and osteoclastogenesis. We investigated the inhibitory effects of RvE1 on osteoclastogenesis and bone resorptio...

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Publicat a:Yonago Acta Med
Autors principals: Funaki, Yoshihiro, Hasegawa, Yasuyuki, Okazaki, Ryota, Yamasaki, Akira, Sueda, Yuriko, Yamamoto, Akihiro, Yanai, Masaaki, Fukushima, Takehito, Harada, Tomoya, Makino, Haruhiko, Shimizu, Eiji
Format: Artigo
Idioma:Inglês
Publicat: Tottori University Faculty of Medicine 2018
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871721/
https://ncbi.nlm.nih.gov/pubmed/29599617
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