Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis

Protein degradation plays important roles in biological processes and is tightly regulated. Further, targeted proteolysis is an emerging research tool and therapeutic strategy. However, proteome-wide technologies to investigate the causes and consequences of protein degradation in biological systems...

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Опубликовано в: :Cell
Главные авторы: Savitski, Mikhail M., Zinn, Nico, Faelth-Savitski, Maria, Poeckel, Daniel, Gade, Stephan, Becher, Isabelle, Muelbaier, Marcel, Wagner, Anne J., Strohmer, Katrin, Werner, Thilo, Melchert, Stephanie, Petretich, Massimo, Rutkowska, Anna, Vappiani, Johanna, Franken, Holger, Steidel, Michael, Sweetman, Gavain M., Gilan, Omer, Lam, Enid Y.N., Dawson, Mark A., Prinjha, Rab K., Grandi, Paola, Bergamini, Giovanna, Bantscheff, Marcus
Формат: Artigo
Язык:Inglês
Опубликовано: Cell Press 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871718/
https://ncbi.nlm.nih.gov/pubmed/29551266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.02.030
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