Ready-to-use food supplement, with or without arginine and citrulline, with daily chloroquine in Tanzanian children with sickle-cell disease: a double-blind, random order crossover trial

BACKGROUND: Sickle-cell disease increases the risk of malnutrition. Low arginine and nitric oxide bioavailability are implicated in morbidity related to sickle-cell disease. Simple interventions are required, especially in low-income settings. We aimed to test the hypotheses that: (1) supplementary...

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Publicat a:Lancet Haematol
Autors principals: Cox, Sharon E, Ellins, Elizabeth A, Marealle, Alphonce I, Newton, Charles R, Soka, Deogratias, Sasi, Philip, Luca Di Tanna, Gian, Johnson, William, Makani, Julie, Prentice, Andrew M, Halcox, Julian P, Kirkham, Fenella J
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Ltd 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871644/
https://ncbi.nlm.nih.gov/pubmed/29548623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2352-3026(18)30020-6
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