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Synthesis of the Privileged 8-Arylmenthol Class by Radical Arylation of Isopulegol

Hydrogen atom transfer (HAT) circumvents a disfavored Friedel-Crafts reaction in the derivatization of the inexpensive monoterpene isopulegol. A variety of readily-prepared aryl and heteroaryl sulfonates undergo a formal hydroarylation to form 8-arylmenthols, privileged scaffolds for asymmetric synt...

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Bibliografski detalji
Izdano u:Org Lett
Glavni autori: Crossley, Steven W. M., Martinez, Ruben M., Guevara-Zuluaga, Sebastián, Shenvi, Ryan A.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871529/
https://ncbi.nlm.nih.gov/pubmed/27175746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b01047
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