A multicenter round robin test of PD-L1 expression assessment in urothelial bladder cancer by immunohistochemistry and RT-qPCR with emphasis on prognosis prediction after radical cystectomy

BACKGROUND: Immunohistochemical PD-L1 assessment is currently used to identify responders towards checkpoint inhibitors although it is limited by inter-observer effects. Here, we conducted a multi-center round robin test to prove the possibility of assessing the PD-L1 status by gene expression to av...

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Vydáno v:Oncotarget
Hlavní autoři: Eckstein, Markus, Wirtz, Ralph M., Pfannstil, Carolin, Wach, Sven, Stoehr, Robert, Breyer, Johannes, Erlmeier, Franziska, Günes, Cagatay, Nitschke, Katja, Weichert, Wilko, Otto, Wolfgang, Keck, Bastian, Eidt, Sebastian, Burger, Maximilian, Taubert, Helge, Wullich, Bernd, Bolenz, Christian, Hartmann, Arndt, Erben, Philipp
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871092/
https://ncbi.nlm.nih.gov/pubmed/29599921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24531
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