Cytotoxic T-cell-related gene expression signature predicts improved survival in muscle-invasive urothelial bladder cancer patients after radical cystectomy and adjuvant chemotherapy

BACKGROUND: Assessment of the immune status of muscle-invasive bladder cancer (MIBC) has previously shown to be prognostically relevant after treatment with curative intent. We conducted this study to develop a clinically applicable immune gene expression assay to predict prognosis and adjuvant chem...

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Pubblicato in:J Immunother Cancer
Autori principali: Eckstein, Markus, Strissel, Pamela, Strick, Reiner, Weyerer, Veronika, Wirtz, Ralph, Pfannstiel, Carolin, Wullweber, Adrian, Lange, Fabienne, Erben, Philipp, Stoehr, Robert, Bertz, Simone, Geppert, Carol Imanuel, Fuhrich, Nicole, Taubert, Helge, Wach, Sven, Breyer, Johannes, Otto, Wolfgang, Burger, Maximilian, Bolenz, Christian, Keck, Bastian, Wullich, Bernd, Hartmann, Arndt, Sikic, Danijel
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2020
Soggetti:
Immunotherapy Biomarkers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253053/
https://ncbi.nlm.nih.gov/pubmed/32448798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000162
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