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FC-99 ameliorates sepsis-induced liver dysfunction by modulating monocyte/macrophage differentiation via Let-7a related monocytes apoptosis
BACKGROUND: The liver is a vital target for sepsis-related injury, leading to inflammatory pathogenesis, multiple organ dysfunction and high mortality rates. Monocyte-derived macrophage transformations are key events in hepatic inflammation. N(1)-[(4-methoxy)methyl]-4-methyl-1,2-benzenediamine (FC-9...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5871089/ https://ncbi.nlm.nih.gov/pubmed/29599918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24127 |
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