Long-term delivery of brain-derived neurotrophic factor (BDNF) from nanoporous silica nanoparticles improves the survival of spiral ganglion neurons in vitro

Sensorineural hearing loss (SNHL) can be overcome by electrical stimulation of spiral ganglion neurons (SGNs) via a cochlear implant (CI). Restricted CI performance results from the spatial gap between the SGNs and the electrode, but the efficacy of CI is also limited by the degeneration of SGNs as...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Schmidt, Nadeschda, Schulze, Jennifer, Warwas, Dawid P., Ehlert, Nina, Lenarz, Thomas, Warnecke, Athanasia, Behrens, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870973/
https://ncbi.nlm.nih.gov/pubmed/29584754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194778
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