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Degenerate codon mixing for PCR-based manipulation of highly repetitive sequences

OBJECTIVE: Repeat expansion of polyglutamine tracks leads to a group of inherited human neurodegenerative disorders. Studying such repetitive sequences is required to gain insight into the pathophysiology of these diseases. PCR-based manipulation of repetitive sequences, however, is challenging due...

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Detalhes bibliográficos
Publicado no:BMC Res Notes
Main Authors: Ratnayake, Dhanushika, Newman, Morgan, Lardelli, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870680/
https://ncbi.nlm.nih.gov/pubmed/29587822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-018-3298-5
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