A scalable moment-closure approximation for large-scale biochemical reaction networks

MOTIVATION: Stochastic molecular processes are a leading cause of cell-to-cell variability. Their dynamics are often described by continuous-time discrete-state Markov chains and simulated using stochastic simulation algorithms. As these stochastic simulations are computationally demanding, ordinary...

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Bibliografske podrobnosti
izdano v:Bioinformatics
Main Authors: Kazeroonian, Atefeh, Theis, Fabian J, Hasenauer, Jan
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Ismb/Eccb 2017: The 25th Annual Conference Intelligent Systems for Molecular Biology Held Jointly with the 16th Annual European Conference on Computational Biology, Prague, Czech Republic, July 21–25, 2017
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870627/
https://ncbi.nlm.nih.gov/pubmed/28881983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx249
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