Pyridoxine 5′-phosphate oxidase is a novel therapeutic target and regulated by the TGF-β signalling pathway in epithelial ovarian cancer

Pyridoxine 5′-phosphate oxidase (PNPO) is an enzyme that converts pyridoxine 5′-phosphate into pyridoxal 5′-phosphate (PLP), an active form of vitamin B6 implicated in several types of cancer. However, the role of PNPO and its regulatory mechanism in epithelial ovarian cancer (EOC) are unknown. In t...

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Argitaratua izan da:Cell Death Dis
Egile Nagusiak: Zhang, Lingyun, Zhou, Daibing, Guan, Wencai, Ren, Weimin, Sun, Wenwen, Shi, Jimin, Lin, Qunbo, Zhang, Jinguo, Qiao, Tiankui, Ye, Yulong, Wu, Yun, Zhang, Yaning, Zuo, Xulei, Connor, Kristin L, Xu, Guoxiong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870590/
https://ncbi.nlm.nih.gov/pubmed/29238081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0050-3
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